Join Our clinical study

Led by Surgeons, for Surgeons

Led by Surgeons, for Surgeons

Join a Landmark Multicenter Study

Vital360Rx is launching one of the largest real-world clinical nutrition studies ever conducted in spine and orthopedic surgery. We are inviting 20–25 high-performing surgeons to participate in this next evolution of surgical care

Led by Dr. Brett Schlifka (Neurosurgery/Spine) and Dr. Milad Alam (Orthopedic Spine), this prospective outcome study aims to quantify the measurable benefits of optimized surgical nutrition using the Vital360™ system (Core360™ Protein + Comfort360™ Recovery Support)

Highlights of This Study

Opportunity includes:

Help Answer a Clear, Actionable Question

Does structured nutritional support before and after surgery measurably improve surgical outcomes?

Meaningful Contribution to Surgical Science

Be part of a 500–1,000 patient, multisite, observational outcomes study evaluating the impact of perioperative nutrition on recovery, inflammation, muscle preservation, immune function, and overall surgical resilience

Zero Workload for Surgeons

We handle everything — patient onboarding, compliance tracking, supplement delivery and outcome collection. Your only requirement: email us the patient’s name & contact information

Essential Study Breakdown

Clinical Overview

Study Purpose

To evaluate whether enhanced perioperative nutrition with Vital360™ improves key biomarkers and clinical outcomes in surgical patients.

Study Enrollment / Duration

12-week study
20–25 surgeons
25 patients per surgeon
Total sample size: 500–1,000 patients

Supplement Protocol

Patients are directed to take: CORE360 + COMFORT360 for 45-60 Days (total days pre and post surgery)

Study Overview

Vital360™ focuses on surgical markers
proven to correlate with patient outcomes,
complication risk, length of stay, and
healing trajectory.

Key Clinical Markers That Drive Surgical Outcomes

Primary Biomarkers

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  • Pre-Albumin
    Nutritional status and protein adequacy.

  • Albumin
    Nutritional risk and wound healing.

  • CRP
    Systemic inflammation.

  • ESR
    Inflammatory burden.

  • Procalcitonin
    Infection and immune response.

  • 25-Hydroxy Vitamin D
    Bone healing, immunity, and complication risk.

Real-World Patient Benefits That Matter Most

Secondary Functional Outcomes

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  • Bone Healing & Fusion Support
    Supports bone repair and surgical fusion.

  • Muscle Preservation
    Helps maintain muscle mass during recovery.

  • Mobility, Stamina & Energy
    Enhances functional movement, endurance, and overall vitality.

  • Patient-Reported Recovery & Well-Being
    Improves patient-perceived healing and overall recovery experience.

Ideal Surgeon Profile for Study Participation

Who Should Apply

  • Spine or Orthopedic Surgeons
    Surgeons performing spine or orthopedic procedures.

  • Belief in Nutritional Impact
    Surgeons who believe nutritional status influences surgical outcomes.

  • Evidence-Based Innovators
    Surgeons interested in contributing to scientific advancement.

  • Zero-Burden Study Participation
    Ideal for surgeons who prefer a study requiring no added clinic workload.

Spots are limited

Join the VITAL360Rx Clinical Outcomes Team Contact Vital360Rx now to join this Landmark Study.

Request a call: 561-810-7565
Apply to Participate: support@vital360rx.com